Wednesday, February 6, 2013

Pringles pop boosts Kellogg's finances

NEW YORK (AP) ? Kellogg reported a fourth-quarter loss on a pension-related charge, but its underlying earnings rose as its recently acquired Pringles chips helped boost sales.

The maker of Froot Loops, Eggo waffles and Pop Tarts said net sales for the period rose 18 percent to $3.56 billion. Sales of existing products rose 5 percent.

However, the company said a new accounting method for its pensions affected results for the quarter. Under the new method, Kellogg Co. lost $32 million, or 9 cents per share, for the period. That compares with a loss of $195 million, or 54 cents per share, for last year's revised results.

Not including one-time items, the company said underlying earnings were 67 cents per share.

Source: http://news.yahoo.com/pringles-pop-boosts-kelloggs-finances-133438104--finance.html

amanda bynes arrested f 18 jet crash in virginia beach john tortorella nicki minaj beez in the trap video food network good friday

Takeover costs dent NYSE Euronext's Q4 profit

PARIS (AP) ? Exchange operator NYSE Euronext says its net income fell 75 percent in the fourth quarter of last year compared to a year earlier on the back of costs related to its upcoming takeover and debt refinancing.

In the last quarter of 2012, the owner of the New York Stock Exchange earned $28 million, compared with $110 million in the fourth quarter of 2011.

The company says Tuesday that excluding charges related to write-offs in preparation for its acquisition by Intercontinental Exchange and the refinancing, its earnings would have been $105 million against $130 million the year before.

Its 2012 earnings were down 29 percent at $462 million on falling trading volumes, largely related to the exceptional volatility that existed in markets in 2011.

Source: http://news.yahoo.com/takeover-costs-dent-nyse-euronexts-q4-profit-082233182--finance.html

oolong tea survivor one world lil kim progeria what will my baby look like gary carter died cmas

Tuesday, February 5, 2013

Bill Clinton to speak at Ed Koch's funeral in NYC

FILE - In this Dec. 10, 2012 file photo, former New York City Mayor Ed Koch says goodbye to reporters as he gets in his car after being released from the hospital in New York. Koch died Friday, Feb. 1, 2013 from congestive heart failure, spokesman George Arzt said. He was 88. (AP Photo/Seth Wenig, File)

FILE - In this Dec. 10, 2012 file photo, former New York City Mayor Ed Koch says goodbye to reporters as he gets in his car after being released from the hospital in New York. Koch died Friday, Feb. 1, 2013 from congestive heart failure, spokesman George Arzt said. He was 88. (AP Photo/Seth Wenig, File)

In this Sept. 11, 1985 file photo, New York Mayor Ed Koch raises his arms in victory at the Sheraton Centre in New York after winning the Democratic primary in his bid for a third four-year term. Koch died Friday, Feb. 1, 2013 from congestive heart failure, spokesman George Arzt said. He was 88. (AP Photo/Mario Suriani, file)

Workers at the Trinity Church Cemetary prepare former New York City mayor Ed Koch's gravesite, Friday, February 1, 2012, in the Washington Heights neighborhood of New York. Koch, who was New York's mayor for three terms from 1978 to 1989, died early Friday morning from congestive heart failure. He was 88 years old. (AP Photo/John Minchillo)

The American flag flies at half-staff outside City Hall to honor the death of former New York City Mayor Ed Koch, Friday, Feb. 1, 2012, in New York. Koch, the combative politician who rescued the city from near-financial ruin during three City Hall terms, died Friday morning of congestive heart failure at age 88. (AP Photo/John Minchillo)

(AP) ? Ed Koch is being remembered as the quintessential New Yorker ? an admired but tough, colorful former mayor who will be honored at his funeral by former President Bill Clinton.

At the service Monday morning at Manhattan's Temple Emanu-El, mourners will also hear about Koch's other fierce loyalty: Israel. The Israeli consul general is set to speak, along with New York Mayor Michael Bloomberg.

Clinton interrupted a trip to Japan to return to New York for the funeral, according to Koch spokesman George Arzt.

He said Koch was a friend of both Bill and Hillary Rodham Clinton, and was helpful during her successful campaign for the U.S. Senate from New York. Koch also backed Hillary Clinton in her presidential run.

Bill Clinton will serve as a representative for President Barack Obama at the funeral.

Koch died Friday of congestive heart failure at age 88.

Friends from his weekly Greenwich Village luncheon gathering got together on Saturday, two weeks after his last meal with them.

The funeral will be held at one of the nation's most prominent synagogues, a Reform Jewish congregation on Fifth Avenue. Bloomberg is a member, as are comedian Joan Rivers and former New York Gov. Eliot Spitzer.

Koch led his city for 12 years, with a brash, humor-tinged style that came to personify the New York of the 1980s.

The Democratic mayor is credited with helping save New York from its economic crisis in the 1970s and leading it to financial rebirth. But during his three terms as mayor, he also faced racial tensions and corruption among political allies, as well as the AIDS epidemic, homelessness and urban crime.

In his weekly radio address, Bloomberg called Koch "our most tireless, fearless, and guileless civic crusader."

The mayor said his predecessor's "tough, determined leadership and responsible fiscal stewardship ... helped lift the city out of its darkest days and set it on course for an incredible comeback."

He added, "When someone needed a good kick in the rear, he gave it to them."

Koch lost the Democratic nomination for mayor in 1989 to David Dinkins, who succeeded him.

Koch said he was defeated "because of longevity." In his words, "people get tired of you."

But as the votes were coming in, he said he told himself, "I'm free at last."

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/386c25518f464186bf7a2ac026580ce7/Article_2013-02-03-Koch-Funeral/id-d44843772bc1480eb5043ff0d544f750

giants super bowl 2012 half time show halftime show 2012 kelly clarkson super bowl 2012 ok go peyton manning super bowl nsx

Oh the drama! Super Ads go epic

NEW YORK (AP) ? Super Bowl ads have morphed into soap operas.

Dwayne "The Rock" Johnson shrugged off aliens and other villains so he could get more milk for his kids at breakfast in a Super Bowl spot for the Milk Processor Education Program. Anheuser-Busch's commercial told the story of a baby Clydesdale growing up and returning to his owner for a heartfelt hug years later. And a Jeep ad portrayed the trials and triumphs of families waiting for their return of family members.

The reason for all the drama? With 30-second spots going for as much as $4 million this year and more than 111 million viewers expected to tune in, marketers are constantly looking for ways to make their ads stand out. And it's increasingly difficult to capture viewers' attention in between plays.

"A lot of advertisers are running long commercials to tell these stories that engage people often in a very emotional way," said Tim Calkins, clinical professor of marketing at the Kellogg School of Management at Northwestern. "These spots that tell stories really stand out in the clutter."

TEAR-JERKING MINI EPICS

Chrysler started the long-format commercial trend last year, with a two-minute spot starring Clint Eastwood that became very popular.

This year, Chrysler led the trend again with its two-minute salute to troops and their families. The ad featured Oprah Winfrey reading a letter from the Jeep brand to encourage families to stay hopeful.

"Wendy Ochoa, a high school teacher who lives in Novi, Michigan, said the ad was very emotional. "It tugs on your heartstrings, how can it not," Ochoa, 44, said.

Audi's 60-second ad in the first quarter, that featured an ending that was voted on by viewers prior to the game, showed the story of a boy gaining confidence from driving his father's Audi to the prom, kissing the prom queen and getting decked by the prom king.

The Audi mini-epic was a favorite of Super Bowl viewer Stephanie Bice, 39, a business development director in Oklahoma City.

"It was fun and whimsical," Bice said.

Meanwhile, Anheuser-Busch pulled at heartstrings with a spot about a baby Clydesdale growing up and moving away from his farm and his trainer. The horse remembered the trainer after returning for a parade, and raced to hug him.

"The Budweiser commercial with the Clydesdale made me cry," said Wendy Ponzo, 49, who was watching the game in Pont Pleasant, N.J. "I can relate to that."

COMEDY GOES LONG

Not all of the storytelling ads were dramatic, though.

Samsung's two-minute ad showed Seth Rogen ("The Guilt Trip" and Paul Rudd ("Role Models") getting called in to do a "Next Big Thing" ad for Samsung. But they're agitated once they realize that they're sharing the spotlight. LeBron James, an NBA basketball player for the Miami Heat, makes a cameo, appearing on a tablet.

The ad won over some fans in the ad world.

"I could watch the Samsung ad over and over again," said David Berkowitz, vice president at digital marketing agency 360i. "It's as good as any Seth Rogen movie."

Budweiser, a long-time Super Bowl advertiser, also told mini-movies in its two of its ads. One showed rival 49ers and Ravens fans each creating a voodoo doll for the other team with the help of R&B legend Stevie Wonder. In the other ad, fans go to great lengths to curse a rival fan's "lucky chair."

"It's only weird if it doesn't work," reads the copy.

And Mercedes-Benz's 90-second ad had a Faustian plot.

A devilish Willem Dafoe ("Spider-Man") shows a man everything that comes with a Mercedes-Benz CLX: A date with supermodel Kate Upton, dancing with Usher, driving around with beautiful girls, getting on the cover of magazines including Vanity Fair and GQ, getting to drive on a racetrack.

He almost signs his soul away for the car. But then he sees a billboard that says the car starts at $29,900, and doesn't sign.

Source: http://news.yahoo.com/oh-drama-super-ads-epic-040414360--finance.html

did the groundhog see his shadow Chris Kyle super bowl commercials Ray Lewis Murder UFC 156 my bloody valentine what time does the superbowl start

Monday, February 4, 2013

Caught in the act: Researchers capture key moments in cell death

Feb. 2, 2013 ? Scientists at the Walter and Eliza Hall Institute have for the first time visualised the molecular changes in a critical cell death protein that force cells to die.

The finding provides important insights into how cell death occurs, and could lead to new classes of medicines that control whether diseased cells live or die.

Cell death, called apoptosis, is important for controlling the number of cells in the body. Defects in cell death have been linked to the development of diseases such as cancer and neurodegenerative conditions. Insufficient cell death can cause cancer by allowing cells to become immortal while excessive cell death of neurons may be a cause of neurodegenerative conditions.

Dr Peter Czabotar, Professor Peter Colman and colleagues in the institute's Structural Biology division, together with Dr Dana Westphal from the institute's Molecular Genetics of Cancer division, made the discovery which is published in the latest edition of the journal Cell.

Dr Czabotar said activation of the protein Bax had long been known to be an important event leading to apoptosis, but until now it was not known how this activation occurred. "One of the key steps in cell death is that holes are punched into a membrane in the cell, the mitochondrial membrane," Dr Czabotar said. "Once this happens the cell is going to go on and die. Bax is responsible for punching the holes in the mitochondrial membrane and visualising its activation brings us a step closer to understanding the mechanics of cell death."

Using the Australian Synchrotron, Dr Czabotar and colleagues were able to obtain detailed three-dimensional images of Bax changing shape as it moved from its inactive to active form. The active form ruptures mitochondrial membranes, removing the cell's energy supply and causing cell death.

"By using the powerful X-ray beams created by the synchrotron, we obtained structures of Bax that were really exciting," Dr Czabotar said. "Bax is activated when small protein fragments called BH3-peptides bind to it. We saw that these peptides open up the Bax molecule like a key unlocking a padlock. This unlocked form of Bax can bind to another Bax molecule, which can then form larger Bax complexes that can go on to break up membranes in the cell.

"As well as explaining the detail of how cell death occurs, our research could provide clues about how to design potential new therapeutic agents that target Bax," Dr Czabotar said. "Now that we can see how Bax changes its shape to move from the inactive to the active form, it may be possible to block Bax activation, to prevent cell death in conditions such as neurodegenerative disorders, where illness is caused by excessive cell death. Similarly, agents that drive Bax into its active form could force immortal cells such as cancer cells to die, providing the basis for a potential new class of anti-cancer agents."

The research was supported by the National Health and Medical Research Council, the Australian Research Council, the Australian Cancer Research Foundation, Cancer Council Victoria, the German Research Foundation, the Leukemia and Lymphoma Society (US) and the Victorian Government.

Share this story on Facebook, Twitter, and Google:

Other social bookmarking and sharing tools:


Story Source:

The above story is reprinted from materials provided by Walter and Eliza Hall Institute.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Peter?E. Czabotar, Dana Westphal, Grant Dewson, Stephen Ma, Colin Hockings, W.?Douglas Fairlie, Erinna?F. Lee, Shenggen Yao, Adeline?Y. Robin, Brian?J. Smith, David?C.S. Huang, Ruth?M. Kluck, Jerry?M. Adams, Peter?M. Colman. Bax Crystal Structures Reveal How BH3 Domains Activate Bax and Nucleate Its Oligomerization to Induce Apoptosis. Cell, 2013; 152 (3): 519 DOI: 10.1016/j.cell.2012.12.031

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_environment/~3/IHLdgIdih0Q/130203085132.htm

jeremy lin Sage Stallone Mermaid Body Found Celeste Holm Stephen Covey klimt bastille day

Friday, February 1, 2013

Weekly US jobless aid applications rise to 368K

In this Wednesday, Jan. 16, 2013, photo, perspective job seekers talk with employers during a job fair in Cuyahoga Falls, Ohio. The number of Americans seeking unemployment aid jumped last week, though the increase mostly reflected difficulties the government has seasonally adjusting its numbers. Applications are still at levels signaling modest hiring. (AP Photo/Tony Dejak)

In this Wednesday, Jan. 16, 2013, photo, perspective job seekers talk with employers during a job fair in Cuyahoga Falls, Ohio. The number of Americans seeking unemployment aid jumped last week, though the increase mostly reflected difficulties the government has seasonally adjusting its numbers. Applications are still at levels signaling modest hiring. (AP Photo/Tony Dejak)

In this Tuesday, Jan. 15, 2012, photo, Norma Urbario, left, and America Rodriguez stand in line, holding their resumes, during the job fair that the Miami Marlins hosted at Marlins Park in Miami. The number of Americans seeking unemployment aid jumped last week, though the increase mostly reflected difficulties the government has seasonally adjusting its numbers. Applications are still at levels signaling modest hiring. (AP Photo/J Pat Carter)

(AP) ? The number of Americans seeking unemployment aid rose sharply last week but remained at a level consistent with moderate hiring.

Weekly applications for unemployment benefits leapt 38,000 to a seasonally adjusted 368,000, the Labor Department said Thursday. The increase comes after applications plummeted in the previous two weeks to five-year lows. Applications fell by a combined 45,000 in the second and third weeks of January.

The volatility reflects the government's difficulty adjusting the data to account for layoffs after the holiday shopping season. Job cuts typically spike in the second week in January as retailers dismiss temporary employees hired for the winter holidays. Layoffs then fall in the second half of the month.

The department attempts to adjust for such fluctuations but the January figures can still be volatile. The four-week average, a less volatile measure, ticked up to 352,000, just above a four-year low.

Most economists weren't concerned by the increase.

"This just reverses some of the previous sharp falls without altering the gradual downward trend," said Paul Dales, an economist at Capital Economics.

On Friday, the government is scheduled to issue its January jobs report. Analysts forecast that it will show employers added 155,000 jobs, the same as in December. The unemployment rate is expected to remain at 7.8 percent for the third straight month.

That's consistent with the number of people seeking unemployment aid. Applications fluctuated between 360,000 and 390,000 for most of last year. At the same time, employers added an average of 153,000 jobs a month.

That's just been enough to slowly push down the unemployment rate, which fell 0.7 percentage points last year to 7.8 percent.

The number of people continuing to claim benefits also rose. More than 5.9 million people received benefits in the week ended Jan. 12, the latest data available. That's 250,000 more than the previous week.

Steady hiring is needed to resume economic growth. The government said Wednesday that the economy shrank at an annual rate of 0.1 percent in the October-December quarter, hurt by a sharp cut in defense spending, fewer exports and sluggish growth in company stockpiles.

The contraction points to what is likely to be the biggest headwind for the economy this year: sharp government spending cuts and ongoing budget fights.

The economy will likely expand in the current quarter and is forecast to grow around 2 percent this year as strength in areas like housing and auto sales could partly offset government cutbacks. But looming, across-the-board spending cuts, set to take effect March 1, would weaken a still-precarious recovery.

Two key drivers of growth improved last quarter. Consumer spending, which accounts for 70 percent of economic activity, increased at a faster pace and businesses invested more in equipment and software.

Homebuilders, meanwhile, are stepping up construction to meet rising demand. That could create more construction jobs.

Home prices are rising steadily. That tends to make Americans feel wealthier and more likely to spend. Housing could add as much as 1 percentage point to economic growth this year, some economists estimate.

And auto sales reached their highest level in five years in 2012. That's boosting production and hiring at U.S. automakers and their suppliers.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/f70471f764144b2fab526d39972d37b3/Article_2013-01-31-Unemployment%20Benefits/id-36db2187fd594e49b3884ddff328c7c5

arkansas razorbacks trisomy 18 ozzie guillen ozzie guillen buster posey eric holder eric holder

Stewart Slams the GOP for Their 'Craven Political Calculation' to Win Back the Hispanic Vote

After giving his viewers a little reminder of what the Republicans sounded like during the 2012 Republican presidential primary race and their blatant race baiting and fearmongering over "illegal immigrants" Jon Stewart took Sen. John McCain and his buddies to task for their "craven political calculation" to try to "squeeze out enough votes" to make states like Nevada competitive again with their flip-flop on passing some sort of immigration reform.

Stewart brought on his correspondent Al Madrigal for his input as to whether the Republicans are going to be successful in their endeavor and Madrigal wasn't too optimistic, given that they appear to be holding their noses while doing what's obviously just politically expedient rather than something they actually support and due to the length of time that "Latinos hold grudges" and who are not going to forget any time soon the way they've been treated by Republicans.

When Stewart asked if there was another demographic they might have any more luck with in the future, like African Americans or women, Madrigal's fellow correspondent Jessica Williams interrupted the segment and put in her two cents about the fact that Republicans aren't going to have any luck there either, especially after remarks like those from "legitimate rape" Todd Akin and the House Republicans deciding to hold their annual retreat -- where they were supposed to be focusing on minority outreach -- at a former slave plantation.

Source: http://crooksandliars.com/heather/stewart-slams-gop-their-craven-political-c

rick perry travis barker get back on board rob lowe peyton manning what is sopa marianne gingrich ibooks author